CRISPR

For Genome Editing, Self-Regulation Beats a Government Ban

A breakthrough method that makes editing the genes of living beings relatively easy, called CRISPR, is much in the news these days. So are the many implications—both terrifying and promising—associated with it. The seemingly endless possibilities of genome editing have even the scientific community on edge, and it’s stirring up heated debate about where the ethical limits are. At the moment, most of the calls for restraint in the use of CRISPR are coming directly from scientists, but it won’t be long before government officials or candidates hoping to be elected start airing their opinions about how this field should be regulated. It’s worth taking a moment to consider how different modes of oversight could affect the opportunities afforded us by genome editing.

National Academy of Sciences Wades into CRISPR-Cas9 Debate

In response to growing concerns about the potential application of CRISPR-Cas9 technology, the National Academy of Sciences and the Institute of Medicine are convening an international summit this fall to “explore the scientific, ethical, and policy issues associated with human gene-editing research.” If you think of a genome as a manuscript, full of extraneous, unnecessary, sometimes flat-out harmful material, the CRISPR-Cas9 technique can be likened to an incredibly useful editing tool. In biological circles, the conversation is heated. Some see remarkable opportunities to prevent the kinds of genetic diseases that impact millions of people a year, things like cystic fibrosis, sickle cell, hemophilia, and more. Others see yet another Pandora’s box that could lead to things like designer babies or the unintended genetic mutations that lead to unimaginable consequences.

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